Novel antifungal diketopiperazine from marine fungus.

نویسندگان

  • Hee-Guk Byun
  • Huiping Zhang
  • Masami Mochizuki
  • Kyoko Adachi
  • Yoshikazu Shizuri
  • Won-Jae Lee
  • Se-Kwon Kim
چکیده

Marine fungi producing antifungal compounds were screened against Pyricularia oryzae (P. oryzae), and a metabolite of marine fungus M-3 isolated from laver (Porphyra yezoensis) showed potent activity. Novel diketopiperazine (1) was isolated from the culture extracts, and its structure was elucidated by spectroscopic methods. The MIC of 1 against P. oryzae was 0.36 microM.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 56 2  شماره 

صفحات  -

تاریخ انتشار 2003